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SMILES: Cc1c(ncc2ccccc12)N(Cc1ccc(cc1)C(F)(F)C1CCC1)S(=O)(=O)c1ccc(cc1)C(O)=O

InChI Key: InChIKey=AYJPSEPPHJSUMC-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 151753   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily M member 8


(Homo sapiens (Human))		BDBM151753
PNG
(US8987445, 189)
Show SMILES Cc1c(ncc2ccccc12)N(Cc1ccc(cc1)C(F)(F)C1CCC1)S(=O)(=O)c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C29H26F2N2O4S/c1-19-26-8-3-2-5-22(26)17-32-27(19)33(38(36,37)25-15-11-21(12-16-25)28(34)35)18-20-9-13-24(14-10-20)29(30,31)23-6-4-7-23/h2-3,5,8-17,23H,4,6-7,18H2,1H3,(H,34,35)
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Similars
US Patent
n/an/a 1.70n/an/an/an/an/a37



Mitsubishi Tanabe Pharma Corporation

US Patent


Assay Description
The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...

US Patent US8987445 (2015)


BindingDB Entry DOI: 10.7270/Q2BZ64R5
More data for this
Ligand-Target Pair