BDBM151758 US8987445, 194

SMILES: Cc1c(ncc2ccccc12)N(Cc1cc2c(F)cc(F)cc2s1)S(=O)(=O)c1ccc(cc1)C(O)=O

InChI Key: InChIKey=PSFHBEMQHOEEIA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 151758   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151758 (US8987445, 194) Show SMILES Cc1c(ncc2ccccc12)N(Cc1cc2c(F)cc(F)cc2s1)S(=O)(=O)c1ccc(cc1)C(O)=O Show InChI InChI=1S/C26H18F2N2O4S2/c1-15-21-5-3-2-4-17(21)13-29-25(15)30(36(33,34)20-8-6-16(7-9-20)26(31)32)14-19-12-22-23(28)10-18(27)11-24(22)35-19/h2-13H,14H2,1H3,(H,31,32)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair