null

SMILES: Cc1c(ncc2ccccc12)N(Cc1sc2ccccc2c1Cl)S(=O)(=O)c1ccc(cc1)C(O)=O

InChI Key: InChIKey=UBSAHDBBJIIWCG-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 151761   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151761 (US8987445, 197) Show SMILES Cc1c(ncc2ccccc12)N(Cc1sc2ccccc2c1Cl)S(=O)(=O)c1ccc(cc1)C(O)=O Show InChI InChI=1S/C26H19ClN2O4S2/c1-16-20-7-3-2-6-18(20)14-28-25(16)29(15-23-24(27)21-8-4-5-9-22(21)34-23)35(32,33)19-12-10-17(11-13-19)26(30)31/h2-14H,15H2,1H3,(H,30,31)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair