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SMILES: COC(c1ccc(CN(c2ncc3ccccc3c2C)S(=O)(=O)c2ccc(cc2)C(O)=O)cc1)(C(F)(F)F)C(F)(F)F

InChI Key: InChIKey=VBSSIHWIIXNRLR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 151785   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily M member 8


(Homo sapiens (Human))		BDBM151785
PNG
(US8987445, 221)
Show SMILES COC(c1ccc(CN(c2ncc3ccccc3c2C)S(=O)(=O)c2ccc(cc2)C(O)=O)cc1)(C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C28H22F6N2O5S/c1-17-23-6-4-3-5-20(23)15-35-24(17)36(42(39,40)22-13-9-19(10-14-22)25(37)38)16-18-7-11-21(12-8-18)26(41-2,27(29,30)31)28(32,33)34/h3-15H,16H2,1-2H3,(H,37,38)
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Similars
US Patent
n/an/a 1.70n/an/an/an/an/a37



Mitsubishi Tanabe Pharma Corporation

US Patent


Assay Description
The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...

US Patent US8987445 (2015)


BindingDB Entry DOI: 10.7270/Q2BZ64R5
More data for this
Ligand-Target Pair