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SMILES: FC(F)(F)c1c(ncc2ccccc12)N(Cc1ccc(c(Cl)c1)C(F)(F)C1CC1)S(=O)(=O)c1ccc(cc1)C(=O)O[Na]

InChI Key: InChIKey=AFSGKCFDHIQJOP-UHFFFAOYSA-M

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 151797   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily M member 8


(Homo sapiens (Human))		BDBM151797
PNG
(US8987445, 233)
Show SMILES FC(F)(F)c1c(ncc2ccccc12)N(Cc1ccc(c(Cl)c1)C(F)(F)C1CC1)S(=O)(=O)c1ccc(cc1)C(=O)O[Na]
Show InChI InChI=1S/C28H20ClF5N2O4S.Na/c29-23-13-16(5-12-22(23)27(30,31)19-8-9-19)15-36(41(39,40)20-10-6-17(7-11-20)26(37)38)25-24(28(32,33)34)21-4-2-1-3-18(21)14-35-25;/h1-7,10-14,19H,8-9,15H2,(H,37,38);/q;+1/p-1
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Similars
US Patent
n/an/a 0.900n/an/an/an/an/a37



Mitsubishi Tanabe Pharma Corporation

US Patent


Assay Description
The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...

US Patent US8987445 (2015)


BindingDB Entry DOI: 10.7270/Q2BZ64R5
More data for this
Ligand-Target Pair