null

SMILES: OS(=O)(=O)c1ccc2NC(=O)\C(=N/Nc3ccccc3[N+]([O-])=O)c2c1

InChI Key: InChIKey=UNCWHIJFMMDYME-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 152151   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM152151 (US8987474, HL1-056 (NSC-117199) ) Show SMILES OS(=O)(=O)c1ccc2NC(=O)\C(=N/Nc3ccccc3[N+]([O-])=O)c2c1 Show InChI InChI=1S/C14H10N4O6S/c19-14-13(17-16-11-3-1-2-4-12(11)18(20)21)9-7-8(25(22,23)24)5-6-10(9)15-14/h1-7,16H,(H,15,17,19)(H,22,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.99E+3	n/a	n/a	n/a	n/a	n/a	n/a
Egyptian Russian University Curated by ChEMBL					Assay Description Inhibition of human GST-tagged Shp2 (205 to 593 residues) expressed Escherichia coli DH5alpha assessed as inhibition of PTP activity using DiFMUP as ...				Eur J Med Chem 122: 366-381 (2016) Article DOI: 10.1016/j.ejmech.2016.06.034 BindingDB Entry DOI: 10.7270/Q2154K1N
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM152151 (US8987474, HL1-056 (NSC-117199) ) Show SMILES OS(=O)(=O)c1ccc2NC(=O)\C(=N/Nc3ccccc3[N+]([O-])=O)c2c1 Show InChI InChI=1S/C14H10N4O6S/c19-14-13(17-16-11-3-1-2-4-12(11)18(20)21)9-7-8(25(22,23)24)5-6-10(9)15-14/h1-7,16H,(H,15,17,19)(H,22,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.73E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of South Florida; H. Lee Moffitt Cancer Center and Research Institute, Inc. US Patent					Assay Description NSC-87877 ranked among top 10% (175th) of the compounds with the best GLIDE scores for the docking to the human Shp2 PTP domain in our virtual screen...				US Patent US8987474 (2015) BindingDB Entry DOI: 10.7270/Q2ZS2V61
					More data for this Ligand-Target Pair