BDBM152777 4-(3-(Piperidin-1-yl)propoxy)-N-(m-tolyl)-2-hydroxybenzamide (10b)

SMILES: Cc1cccc(NC(=O)c2ccc(OCCCN3CCCCC3)cc2O)c1

InChI Key: InChIKey=MCMVFLOVLROIPK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 152777   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
EGFR (Homo sapiens (Human))	BDBM152777 (4-(3-(Piperidin-1-yl)propoxy)-N-(m-tolyl)-2-hydrox...) Show SMILES Cc1cccc(NC(=O)c2ccc(OCCCN3CCCCC3)cc2O)c1 Show InChI InChI=1S/C22H28N2O3/c1-17-7-5-8-18(15-17)23-22(26)20-10-9-19(16-21(20)25)27-14-6-13-24-11-3-2-4-12-24/h5,7-10,15-16,25H,2-4,6,11-14H2,1H3,(H,23,26)	PDB MMDB B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22.4	n/a	n/a	n/a	n/a	n/a	25
Anhui University of Chinese Medicine					Assay Description The experiments were performed according to the instructions of the manufacturer. The EGFR TK activity was performed using Kinase-Glo Plus luminescen...				Chem Biol Drug Des 85: 280-9 (2015) Article DOI: 10.1111/cbdd.12383 BindingDB Entry DOI: 10.7270/Q2JD4VJR
					More data for this Ligand-Target Pair