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SMILES: Cl.FC(F)(F)c1ccc(COc2ccn(-c3ccn4c5CNCCc5nc4c3)c(=O)c2)cn1

InChI Key: InChIKey=UORIFFYDKJPLMC-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 153258   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM153258
PNG
(US8993765, 25)
Show SMILES Cl.FC(F)(F)c1ccc(COc2ccn(-c3ccn4c5CNCCc5nc4c3)c(=O)c2)cn1
Show InChI InChI=1S/C22H18F3N5O2.ClH/c23-22(24,25)19-2-1-14(11-27-19)13-32-16-5-8-29(21(31)10-16)15-4-7-30-18-12-26-6-3-17(18)28-20(30)9-15;/h1-2,4-5,7-11,26H,3,6,12-13H2;1H
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Similars
US Patent
 3.32E+3n/an/an/an/an/an/a7.4n/a



Albany Molecular Research, Inc.

US Patent


Assay Description
Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...

US Patent US8993765 (2015)


BindingDB Entry DOI: 10.7270/Q2QZ28Q8
More data for this
Ligand-Target Pair