BDBM153276 (Z)-2-(2,5-Dimethoxybenzylidene)-4-methoxybenzofuran-3(2H)-one (4a)
SMILES: COc1ccc(OC)c(\C=C2/Oc3cccc(OC)c3C2=O)c1
InChI Key: InChIKey=LHTFOGYWWNWPIC-YBEGLDIGSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat)) | BDBM153276 ((Z)-2-(2,5-Dimethoxybenzylidene)-4-methoxybenzofur...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.78E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pontificia Universidad Católica de Chile | Assay Description Briefly, a crude rat brain mitochondrial suspension (male Sprague¿Dawley rats weighing 180¿220 g, killed by decapitation) was used as protein source.... | Chem Biol Drug Des 85: 685-95 (2015) Article DOI: 10.1111/cbdd.12458 BindingDB Entry DOI: 10.7270/Q2BP01HR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoamine oxidase (Rattus norvegicus (rat)) | BDBM153276 ((Z)-2-(2,5-Dimethoxybenzylidene)-4-methoxybenzofur...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pontificia Universidad Católica de Chile | Assay Description Briefly, a crude rat brain mitochondrial suspension (male Sprague¿Dawley rats weighing 180¿220 g, killed by decapitation) was used as protein source.... | Chem Biol Drug Des 85: 685-95 (2015) Article DOI: 10.1111/cbdd.12458 BindingDB Entry DOI: 10.7270/Q2BP01HR | |||||||||||
More data for this Ligand-Target Pair |