BDBM154034 US9012443, 27
SMILES: Clc1ccc(c(c1)-c1cn[nH]c1)-c1cccc2cc(ccc12)S(=O)(=O)Nc1ncns1
InChI Key: InChIKey=FIUXOLTZOKZTOV-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human)) | BDBM154034 (US9012443, 27) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc. US Patent | Assay Description 293 cells stably transfected with Nav 1.5 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology system acco... | US Patent US9012443 (2015) BindingDB Entry DOI: 10.7270/Q2N0158J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human)) | BDBM154034 (US9012443, 27) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc. US Patent | Assay Description 293 Cells stably transfected with either Nav 1.7 or Nav 1.5 were recorded in population patch-clamp mode with the IonWorks Quattro automated electrop... | US Patent US9012443 (2015) BindingDB Entry DOI: 10.7270/Q2N0158J | |||||||||||
More data for this Ligand-Target Pair |