null

SMILES: CSc1cccc(NC(=O)[C@@H]2CCCN2S(=O)(=O)c2ccc(cc2)C(F)(F)F)c1

InChI Key: InChIKey=WOQNVEBUHZAZDX-KRWDZBQOSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 154929   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin receptor type 2 (Homo sapiens (Human))	BDBM154929 (US9000029, 8) Show SMILES CSc1cccc(NC(=O)[C@@H]2CCCN2S(=O)(=O)c2ccc(cc2)C(F)(F)F)c1 Show InChI InChI=1S/C19H19F3N2O3S2/c1-28-15-5-2-4-14(12-15)23-18(25)17-6-3-11-24(17)29(26,27)16-9-7-13(8-10-16)19(20,21)22/h2,4-5,7-10,12,17H,3,6,11H2,1H3,(H,23,25)/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	37
Actelion Pharmaceuticals Ltd. US Patent					Assay Description Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...				US Patent US9000029 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B3F
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Homo sapiens (Human))	BDBM154929 (US9000029, 8) Show SMILES CSc1cccc(NC(=O)[C@@H]2CCCN2S(=O)(=O)c2ccc(cc2)C(F)(F)F)c1 Show InChI InChI=1S/C19H19F3N2O3S2/c1-28-15-5-2-4-14(12-15)23-18(25)17-6-3-11-24(17)29(26,27)16-9-7-13(8-10-16)19(20,21)22/h2,4-5,7-10,12,17H,3,6,11H2,1H3,(H,23,25)/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	37
Actelion Pharmaceuticals Ltd. US Patent					Assay Description Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...				US Patent US9000029 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B3F
					More data for this Ligand-Target Pair