BDBM154937 US9000029, 16

SMILES: COc1ccc(cc1)S(=O)(=O)N1CCC[C@H]1C(=O)Nc1cc(Cl)cc(Cl)c1

InChI Key: InChIKey=MYGUQPLFXGIMOL-KRWDZBQOSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 154937   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin receptor type 2 (Homo sapiens (Human))	BDBM154937 (US9000029, 16) Show SMILES COc1ccc(cc1)S(=O)(=O)N1CCC[C@H]1C(=O)Nc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C18H18Cl2N2O4S/c1-26-15-4-6-16(7-5-15)27(24,25)22-8-2-3-17(22)18(23)21-14-10-12(19)9-13(20)11-14/h4-7,9-11,17H,2-3,8H2,1H3,(H,21,23)/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	37
Actelion Pharmaceuticals Ltd. US Patent					Assay Description Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...				US Patent US9000029 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B3F
					More data for this Ligand-Target Pair
Orexin receptor type 1 (Homo sapiens (Human))	BDBM154937 (US9000029, 16) Show SMILES COc1ccc(cc1)S(=O)(=O)N1CCC[C@H]1C(=O)Nc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C18H18Cl2N2O4S/c1-26-15-4-6-16(7-5-15)27(24,25)22-8-2-3-17(22)18(23)21-14-10-12(19)9-13(20)11-14/h4-7,9-11,17H,2-3,8H2,1H3,(H,21,23)/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	37
Actelion Pharmaceuticals Ltd. US Patent					Assay Description Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...				US Patent US9000029 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B3F
					More data for this Ligand-Target Pair