null

SMILES: COc1ccc(C)cc1S(=O)(=O)N1CCC[C@H]1C(=O)Nc1cc(C)cc(C)c1

InChI Key: InChIKey=NKQVPJZIEULYJM-SFHVURJKSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 154969   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin receptor type 2 (Homo sapiens (Human))	BDBM154969 (US9000029, 48) Show SMILES COc1ccc(C)cc1S(=O)(=O)N1CCC[C@H]1C(=O)Nc1cc(C)cc(C)c1 Show InChI InChI=1S/C21H26N2O4S/c1-14-7-8-19(27-4)20(13-14)28(25,26)23-9-5-6-18(23)21(24)22-17-11-15(2)10-16(3)12-17/h7-8,10-13,18H,5-6,9H2,1-4H3,(H,22,24)/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	37
Actelion Pharmaceuticals Ltd. US Patent					Assay Description Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...				US Patent US9000029 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B3F
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Homo sapiens (Human))	BDBM154969 (US9000029, 48) Show SMILES COc1ccc(C)cc1S(=O)(=O)N1CCC[C@H]1C(=O)Nc1cc(C)cc(C)c1 Show InChI InChI=1S/C21H26N2O4S/c1-14-7-8-19(27-4)20(13-14)28(25,26)23-9-5-6-18(23)21(24)22-17-11-15(2)10-16(3)12-17/h7-8,10-13,18H,5-6,9H2,1-4H3,(H,22,24)/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	37
Actelion Pharmaceuticals Ltd. US Patent					Assay Description Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...				US Patent US9000029 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B3F
					More data for this Ligand-Target Pair