BDBM155118 US9000183, 4
SMILES:
InChI Key: InChIKey=WSDJYMPBPPNFDL-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta amyloid A4 protein (Homo sapiens (Human)) | BDBM155118 (US9000183, 4) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 176 | n/a | n/a | n/a | n/a | n/a | 37 |
Astrazeneca AB US Patent | Assay Description SH-SY5Y cells were cultured in DMEM/F-12 with Glutamax, 10% FCS and 1% non-essential amino acids and cryopreserved and stored at -140 C. at a concent... | US Patent US9000183 (2015) BindingDB Entry DOI: 10.7270/Q2PR7TQD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM155118 (US9000183, 4) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 516 | n/a | n/a | n/a | n/a | 2.5 | n/a |
Astrazeneca AB US Patent | Assay Description The beta -secretase enzyme used in the TR-FRET is prepared as follows:The cDNA for the soluble part of the human beta -Secretase (AA 1-AA 460) was cl... | US Patent US9000183 (2015) BindingDB Entry DOI: 10.7270/Q2PR7TQD | |||||||||||
More data for this Ligand-Target Pair |