BindingDB logo
myBDB logout

null

SMILES: N[C@H]1CN(CC[C@@H]1c1cc(F)c(F)cc1F)c1cc(ncn1)N1CCn2cc(nc2C1)C(F)(F)F

InChI Key: InChIKey=LTXRTUYGIODUMC-PXAZEXFGSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15525   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dipeptidyl peptidase 4


(Homo sapiens (Human))		BDBM15525
PNG
((3R, 4R)-1-(6-(2-(Trifluoromethyl)-5,6-dihydroimid...)
Show SMILES N[C@H]1CN(CC[C@@H]1c1cc(F)c(F)cc1F)c1cc(ncn1)N1CCn2cc(nc2C1)C(F)(F)F |r|
Show InChI InChI=1S/C22H21F6N7/c23-14-6-16(25)15(24)5-13(14)12-1-2-33(8-17(12)29)19-7-20(31-11-30-19)35-4-3-34-9-18(22(26,27)28)32-21(34)10-35/h5-7,9,11-12,17H,1-4,8,10,29H2/t12-,17+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 3n/an/an/an/an/an/an/an/a



Abbott Laboratories



Assay Description
The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...

J Med Chem 50: 1983-7 (2007)


Article DOI: 10.1021/jm061436d
BindingDB Entry DOI: 10.7270/Q2VQ30XV
More data for this
Ligand-Target Pair