null

SMILES: Fc1cccc(NC(=O)N2CC(C2)Oc2ccc(cc2)-c2ccccc2)c1

InChI Key: InChIKey=HFEFMQVTVZOJLC-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 155356   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM155356 (US10383871, Example 2 | US10918640, Example 2 | US...) Show SMILES Fc1cccc(NC(=O)N2CC(C2)Oc2ccc(cc2)-c2ccccc2)c1 Show InChI InChI=1S/C22H19FN2O2/c23-18-7-4-8-19(13-18)24-22(26)25-14-21(15-25)27-20-11-9-17(10-12-20)16-5-2-1-3-6-16/h1-13,21H,14-15H2,(H,24,26)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	279	n/a	n/a	n/a	n/a	8.2	25
Vernalis (R&D) Ltd. US Patent					Assay Description FAAH activity was determined by measuring the liberation of the highly fluorescent 7-amino, 4-methyl Coumarin (AMC) generated during hydrolysis of th...				US Patent US9006269 (2015) BindingDB Entry DOI: 10.7270/Q2DB80KF
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM155356 (US10383871, Example 2 | US10918640, Example 2 | US...) Show SMILES Fc1cccc(NC(=O)N2CC(C2)Oc2ccc(cc2)-c2ccccc2)c1 Show InChI InChI=1S/C22H19FN2O2/c23-18-7-4-8-19(13-18)24-22(26)25-14-21(15-25)27-20-11-9-17(10-12-20)16-5-2-1-3-6-16/h1-13,21H,14-15H2,(H,24,26)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	279	n/a	n/a	n/a	n/a	n/a	n/a
Vernalis (R&D) Ltd. US Patent					Assay Description Active rat FAAH protein (30-579) was isolated as described in the literature. The coding sequence of amino adds 30-579 of rat FAAH were cloned into t...				US Patent US10918640 (2021)
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM155356 (US10383871, Example 2 | US10918640, Example 2 | US...) Show SMILES Fc1cccc(NC(=O)N2CC(C2)Oc2ccc(cc2)-c2ccccc2)c1 Show InChI InChI=1S/C22H19FN2O2/c23-18-7-4-8-19(13-18)24-22(26)25-14-21(15-25)27-20-11-9-17(10-12-20)16-5-2-1-3-6-16/h1-13,21H,14-15H2,(H,24,26)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	279	n/a	n/a	n/a	n/a	n/a	n/a
Vernalis (R&D) Ltd. US Patent					Assay Description Active rat FAAH protein (30-579) was isolated as described in the literature. The coding sequence of amino acids 30-579 of rat FAAH were cloned into ...				US Patent US10383871 (2019) BindingDB Entry DOI: 10.7270/Q2NV9MNH
					More data for this Ligand-Target Pair