BDBM155365 US10383871, Example 11::US10918640, Example 11::US9006269, 11

SMILES: COCCOc1ccc(OC)c(c1)-c1ccc(OC2CN(C2)C(=O)Nc2cccnn2)nc1

InChI Key: InChIKey=YNZXNGQXSSMPCL-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 155365   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM155365 (US10383871, Example 11 | US10918640, Example 11 | ...) Show SMILES COCCOc1ccc(OC)c(c1)-c1ccc(OC2CN(C2)C(=O)Nc2cccnn2)nc1 Show InChI InChI=1S/C23H25N5O5/c1-30-10-11-32-17-6-7-20(31-2)19(12-17)16-5-8-22(24-13-16)33-18-14-28(15-18)23(29)26-21-4-3-9-25-27-21/h3-9,12-13,18H,10-11,14-15H2,1-2H3,(H,26,27,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	19	n/a	n/a	n/a	n/a	8.2	25
Vernalis (R&D) Ltd. US Patent					Assay Description Human FAAH 1 activity was determined by measuring the liberation of the highly fluorescent 7-amino, 4-methyl Coumarin (AMC) generated during hydrolys...				US Patent US9006269 (2015) BindingDB Entry DOI: 10.7270/Q2DB80KF
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM155365 (US10383871, Example 11 | US10918640, Example 11 | ...) Show SMILES COCCOc1ccc(OC)c(c1)-c1ccc(OC2CN(C2)C(=O)Nc2cccnn2)nc1 Show InChI InChI=1S/C23H25N5O5/c1-30-10-11-32-17-6-7-20(31-2)19(12-17)16-5-8-22(24-13-16)33-18-14-28(15-18)23(29)26-21-4-3-9-25-27-21/h3-9,12-13,18H,10-11,14-15H2,1-2H3,(H,26,27,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Vernalis (R&D) Ltd. US Patent					Assay Description Human FAAH 1 activity was determined by measuring the liberation of the highly fluorescent 7-amino, 4-methyl Coumarin (AMC) generated during hydrolys...				US Patent US10918640 (2021)
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM155365 (US10383871, Example 11 | US10918640, Example 11 | ...) Show SMILES COCCOc1ccc(OC)c(c1)-c1ccc(OC2CN(C2)C(=O)Nc2cccnn2)nc1 Show InChI InChI=1S/C23H25N5O5/c1-30-10-11-32-17-6-7-20(31-2)19(12-17)16-5-8-22(24-13-16)33-18-14-28(15-18)23(29)26-21-4-3-9-25-27-21/h3-9,12-13,18H,10-11,14-15H2,1-2H3,(H,26,27,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Vernalis (R&D) Ltd. US Patent					Assay Description Human FAAH 1 activity was determined by measuring the liberation of the highly fluorescent 7-amino, 4-methyl Coumarin (AMC) generated during hydrolys...				US Patent US10383871 (2019) BindingDB Entry DOI: 10.7270/Q2NV9MNH
					More data for this Ligand-Target Pair