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SMILES: COc1cccc(c1F)-c1ccc(OC2CN(C2)C(=O)Nc2cccnn2)nc1

InChI Key: InChIKey=GQVNLDQKGBHOIC-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 155369   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM155369 (US10383871, Example 19 | US10918640, Example 19 | ...) Show SMILES COc1cccc(c1F)-c1ccc(OC2CN(C2)C(=O)Nc2cccnn2)nc1 Show InChI InChI=1S/C20H18FN5O3/c1-28-16-5-2-4-15(19(16)21)13-7-8-18(22-10-13)29-14-11-26(12-14)20(27)24-17-6-3-9-23-25-17/h2-10,14H,11-12H2,1H3,(H,24,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	26	n/a	n/a	n/a	n/a	8.2	25
Vernalis (R&D) Ltd. US Patent					Assay Description Human FAAH 1 activity was determined by measuring the liberation of the highly fluorescent 7-amino, 4-methyl Coumarin (AMC) generated during hydrolys...				US Patent US9006269 (2015) BindingDB Entry DOI: 10.7270/Q2DB80KF
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM155369 (US10383871, Example 19 | US10918640, Example 19 | ...) Show SMILES COc1cccc(c1F)-c1ccc(OC2CN(C2)C(=O)Nc2cccnn2)nc1 Show InChI InChI=1S/C20H18FN5O3/c1-28-16-5-2-4-15(19(16)21)13-7-8-18(22-10-13)29-14-11-26(12-14)20(27)24-17-6-3-9-23-25-17/h2-10,14H,11-12H2,1H3,(H,24,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Vernalis (R&D) Ltd. US Patent					Assay Description Human FAAH 1 activity was determined by measuring the liberation of the highly fluorescent 7-amino, 4-methyl Coumarin (AMC) generated during hydrolys...				US Patent US10918640 (2021)
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM155369 (US10383871, Example 19 | US10918640, Example 19 | ...) Show SMILES COc1cccc(c1F)-c1ccc(OC2CN(C2)C(=O)Nc2cccnn2)nc1 Show InChI InChI=1S/C20H18FN5O3/c1-28-16-5-2-4-15(19(16)21)13-7-8-18(22-10-13)29-14-11-26(12-14)20(27)24-17-6-3-9-23-25-17/h2-10,14H,11-12H2,1H3,(H,24,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Vernalis (R&D) Ltd. US Patent					Assay Description Human FAAH 1 activity was determined by measuring the liberation of the highly fluorescent 7-amino, 4-methyl Coumarin (AMC) generated during hydrolys...				US Patent US10383871 (2019) BindingDB Entry DOI: 10.7270/Q2NV9MNH
					More data for this Ligand-Target Pair