BDBM155371 US10383871, Example 16::US10918640, Example 16::US9006269, 16

SMILES: Fc1ccccc1-c1ccc(OC2CN(C2)C(=O)Nc2cnccn2)nc1

InChI Key: InChIKey=MXZUCQMCGWGEFM-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 155371   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM155371 (US10383871, Example 16 | US10918640, Example 16 | ...) Show SMILES Fc1ccccc1-c1ccc(OC2CN(C2)C(=O)Nc2cnccn2)nc1 Show InChI InChI=1S/C19H16FN5O2/c20-16-4-2-1-3-15(16)13-5-6-18(23-9-13)27-14-11-25(12-14)19(26)24-17-10-21-7-8-22-17/h1-10,14H,11-12H2,(H,22,24,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	42	n/a	n/a	n/a	n/a	8.2	25
Vernalis (R&D) Ltd. US Patent					Assay Description Human FAAH 1 activity was determined by measuring the liberation of the highly fluorescent 7-amino, 4-methyl Coumarin (AMC) generated during hydrolys...				US Patent US9006269 (2015) BindingDB Entry DOI: 10.7270/Q2DB80KF
					More data for this Ligand-Target Pair
Anandamide amidohydrolase (Homo sapiens (Human))	BDBM155371 (US10383871, Example 16 | US10918640, Example 16 | ...) Show SMILES Fc1ccccc1-c1ccc(OC2CN(C2)C(=O)Nc2cnccn2)nc1 Show InChI InChI=1S/C19H16FN5O2/c20-16-4-2-1-3-15(16)13-5-6-18(23-9-13)27-14-11-25(12-14)19(26)24-17-10-21-7-8-22-17/h1-10,14H,11-12H2,(H,22,24,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
Vernalis (R&D) Ltd. US Patent					Assay Description Human FAAH 1 activity was determined by measuring the liberation of the highly fluorescent 7-amino, 4-methyl Coumarin (AMC) generated during hydrolys...				US Patent US10918640 (2021)
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM155371 (US10383871, Example 16 | US10918640, Example 16 | ...) Show SMILES Fc1ccccc1-c1ccc(OC2CN(C2)C(=O)Nc2cnccn2)nc1 Show InChI InChI=1S/C19H16FN5O2/c20-16-4-2-1-3-15(16)13-5-6-18(23-9-13)27-14-11-25(12-14)19(26)24-17-10-21-7-8-22-17/h1-10,14H,11-12H2,(H,22,24,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
Vernalis (R&D) Ltd. US Patent					Assay Description Human FAAH 1 activity was determined by measuring the liberation of the highly fluorescent 7-amino, 4-methyl Coumarin (AMC) generated during hydrolys...				US Patent US10383871 (2019) BindingDB Entry DOI: 10.7270/Q2NV9MNH
					More data for this Ligand-Target Pair