BDBM15608 CHEMBL353159::N-Methyl,N-propargyl-1H-pyrrole-2-carboxamide::N-methyl-N-(prop-2-yn-1-yl)-1H-pyrrole-2-carboxamide::pyrrole inhibitor 33

SMILES: CN(CC#C)C(=O)c1ccc[nH]1

InChI Key: InChIKey=IKQLCRCMGYGVMD-UHFFFAOYSA-N

Data: 6 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 15608   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoamine oxidase (Bos taurus)	BDBM15608 (CHEMBL353159 | N-Methyl,N-propargyl-1H-pyrrole-2-c...) Show SMILES CN(CC#C)C(=O)c1ccc[nH]1 Show InChI InChI=1S/C9H10N2O/c1-3-7-11(2)9(12)8-5-4-6-10-8/h1,4-6,10H,7H2,2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Padmashri Vikhe Patil College Curated by ChEMBL					Assay Description Inhibition of bovine MAO-A using kinuramine as substrate by fluorometric method				Eur J Med Chem 110: 13-31 (2016) BindingDB Entry DOI: 10.7270/Q2S75J6C
					More data for this Ligand-Target Pair
Monoamine oxidase (Bos taurus)	BDBM15608 (CHEMBL353159 | N-Methyl,N-propargyl-1H-pyrrole-2-c...) Show SMILES CN(CC#C)C(=O)c1ccc[nH]1 Show InChI InChI=1S/C9H10N2O/c1-3-7-11(2)9(12)8-5-4-6-10-8/h1,4-6,10H,7H2,2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	75	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibitory activity against monoamine oxidase A in isolated bovine brain mitochondria				J Med Chem 46: 917-20 (2003) Article DOI: 10.1021/jm0256124 BindingDB Entry DOI: 10.7270/Q20V8C52
					More data for this Ligand-Target Pair
Monoamine Oxidase Type A (MAO-A) (Bos taurus)	BDBM15608 (CHEMBL353159 | N-Methyl,N-propargyl-1H-pyrrole-2-c...) Show SMILES CN(CC#C)C(=O)c1ccc[nH]1 Show InChI InChI=1S/C9H10N2O/c1-3-7-11(2)9(12)8-5-4-6-10-8/h1,4-6,10H,7H2,2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	75	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita di Roma La Sapienza					Assay Description MAO A and MAO B activities were determined spectrophotometrically using kinuramine as substrates. Fluorimetric measurements were recorded with a Perk...				J Med Chem 50: 922-31 (2007) Article DOI: 10.1021/jm060882y BindingDB Entry DOI: 10.7270/Q2GH9G61
					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Bos taurus)	BDBM15608 (CHEMBL353159 | N-Methyl,N-propargyl-1H-pyrrole-2-c...) Show SMILES CN(CC#C)C(=O)c1ccc[nH]1 Show InChI InChI=1S/C9H10N2O/c1-3-7-11(2)9(12)8-5-4-6-10-8/h1,4-6,10H,7H2,2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita di Roma La Sapienza					Assay Description MAO A and MAO B activities were determined spectrophotometrically using kinuramine as substrates. Fluorimetric measurements were recorded with a Perk...				J Med Chem 50: 922-31 (2007) Article DOI: 10.1021/jm060882y BindingDB Entry DOI: 10.7270/Q2GH9G61
					More data for this Ligand-Target Pair
Monoamine oxidase (Bos taurus)	BDBM15608 (CHEMBL353159 | N-Methyl,N-propargyl-1H-pyrrole-2-c...) Show SMILES CN(CC#C)C(=O)c1ccc[nH]1 Show InChI InChI=1S/C9H10N2O/c1-3-7-11(2)9(12)8-5-4-6-10-8/h1,4-6,10H,7H2,2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibitory activity against monoamine oxidase B in isolated bovine brain mitochondria				J Med Chem 46: 917-20 (2003) Article DOI: 10.1021/jm0256124 BindingDB Entry DOI: 10.7270/Q20V8C52
					More data for this Ligand-Target Pair
Amine oxidase (flavin-containing) A (Homo sapiens (Human))	BDBM15608 (CHEMBL353159 | N-Methyl,N-propargyl-1H-pyrrole-2-c...) Show SMILES CN(CC#C)C(=O)c1ccc[nH]1 Show InChI InChI=1S/C9H10N2O/c1-3-7-11(2)9(12)8-5-4-6-10-8/h1,4-6,10H,7H2,2H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.50E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bharati Vidyapeeth Deemed University Curated by ChEMBL					Assay Description Inhibition of MAO-A receptor				Bioorg Med Chem Lett 21: 2419-24 (2011) Article DOI: 10.1016/j.bmcl.2011.02.072 BindingDB Entry DOI: 10.7270/Q2QZ2C6S
					More data for this Ligand-Target Pair