BDBM156340 US9018217, 1-{2-[2-(5,7-Dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-ylmethylsulfanyl)-4-phenyl-imidazol-1-yl]-ethyl}-3-methyl-imidazolidin-2-one::US9592230, 1-{2-[2-(5,7-Dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-ylmethylsulfanyl)-4-phenyl-imidazol-1-yl]-ethyl}-3-methyl-imidazolidin-2-one

SMILES: CN1CCN(CCn2cc(nc2SCc2nc3nc(C)cc(C)n3n2)-c2ccccc2)C1=O

InChI Key: InChIKey=GOBBYECNXDDNMK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 156340   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM156340 (US9018217, 1-{2-[2-(5,7-Dimethyl-[1,2,4]triazolo[1...) Show SMILES CN1CCN(CCn2cc(nc2SCc2nc3nc(C)cc(C)n3n2)-c2ccccc2)C1=O Show InChI InChI=1S/C23H26N8OS/c1-16-13-17(2)31-21(24-16)26-20(27-31)15-33-22-25-19(18-7-5-4-6-8-18)14-30(22)12-11-29-10-9-28(3)23(29)32/h4-8,13-14H,9-12,15H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S US Patent					Assay Description A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...				US Patent US9592230 (2017) BindingDB Entry DOI: 10.7270/Q2CV4KSH
					More data for this Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM156340 (US9018217, 1-{2-[2-(5,7-Dimethyl-[1,2,4]triazolo[1...) Show SMILES CN1CCN(CCn2cc(nc2SCc2nc3nc(C)cc(C)n3n2)-c2ccccc2)C1=O Show InChI InChI=1S/C23H26N8OS/c1-16-13-17(2)31-21(24-16)26-20(27-31)15-33-22-25-19(18-7-5-4-6-8-18)14-30(22)12-11-29-10-9-28(3)23(29)32/h4-8,13-14H,9-12,15H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	25
H. Lundbeck A/S US Patent					Assay Description A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...				US Patent US9018217 (2015) BindingDB Entry DOI: 10.7270/Q2KW5DS1
					More data for this Ligand-Target Pair