BDBM156414 US9023354, AD4-1505

SMILES: COc1ccc(cc1O)C(Nc1cc(C)ccn1)c1ccc2cccnc2c1O

InChI Key: InChIKey=FCTHDIWMHUZDNV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 156414   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM156414 (US9023354, AD4-1505) Show SMILES COc1ccc(cc1O)C(Nc1cc(C)ccn1)c1ccc2cccnc2c1O Show InChI InChI=1S/C23H21N3O3/c1-14-9-11-24-20(12-14)26-21(16-6-8-19(29-2)18(27)13-16)17-7-5-15-4-3-10-25-22(15)23(17)28/h3-13,21,27-28H,1-2H3,(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	25
TBA US Patent					Assay Description The following example describes an assay that measured the ability of compounds to inhibit the binding of p53 to MDM2 using the AlphaScreen assay tec...				US Patent US9023354 (2015) BindingDB Entry DOI: 10.7270/Q26M35KH
					More data for this Ligand-Target Pair