BDBM156686 US9029559, 37

SMILES: Cc1ccccc1[C@H](CC(O)=O)NC(=O)c1cccc(n1)-c1ccccc1

InChI Key: InChIKey=KJBSEFNIMFLOND-FQEVSTJZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 156686   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cathepsin A (CTSA) (Homo sapiens (Human))	BDBM156686 (US9029559, 37) Show SMILES Cc1ccccc1[C@H](CC(O)=O)NC(=O)c1cccc(n1)-c1ccccc1 Show InChI InChI=1S/C22H20N2O3/c1-15-8-5-6-11-17(15)20(14-21(25)26)24-22(27)19-13-7-12-18(23-19)16-9-3-2-4-10-16/h2-13,20H,14H2,1H3,(H,24,27)(H,25,26)/t20-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	130	n/a	n/a	n/a	n/a	5.5	25
SANOFI US Patent					Assay Description The activated cathepsin A was diluted in assay buffer (25 mM MES, pH 5.5, containing 5 mM DTT) and mixed with the test compound (dissolved in assay b...				US Patent US9029559 (2015) BindingDB Entry DOI: 10.7270/Q22V2DW7
					More data for this Ligand-Target Pair