BDBM156726 US9029559, 142

SMILES: Cc1ccccc1[C@H](CC(O)=O)NC(=O)c1cccc(n1)-c1ccccc1Cl

InChI Key: InChIKey=BBTAJYYVNIURAC-FQEVSTJZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 156726   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cathepsin A (CTSA) (Homo sapiens (Human))	BDBM156726 (US9029559, 142) Show SMILES Cc1ccccc1[C@H](CC(O)=O)NC(=O)c1cccc(n1)-c1ccccc1Cl Show InChI InChI=1S/C22H19ClN2O3/c1-14-7-2-3-8-15(14)20(13-21(26)27)25-22(28)19-12-6-11-18(24-19)16-9-4-5-10-17(16)23/h2-12,20H,13H2,1H3,(H,25,28)(H,26,27)/t20-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	5.5	25
SANOFI US Patent					Assay Description The activated cathepsin A was diluted in assay buffer (25 mM MES, pH 5.5, containing 5 mM DTT) and mixed with the test compound (dissolved in assay b...				US Patent US9029559 (2015) BindingDB Entry DOI: 10.7270/Q22V2DW7
					More data for this Ligand-Target Pair