BindingDB logo
myBDB logout

null

SMILES: CC1(C)C(=O)Nc2nc(ncc12)-n1nc(Cc2ccccc2F)c2cc(F)ccc12

InChI Key: InChIKey=SOLRITZESDYLKR-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 157140   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cGMP-specific 3',5'-cyclic phosphodiesterase


(Homo sapiens (Human))		BDBM157140
PNG
(US9023849, 8)
Show SMILES CC1(C)C(=O)Nc2nc(ncc12)-n1nc(Cc2ccccc2F)c2cc(F)ccc12
Show InChI InChI=1S/C22H17F2N5O/c1-22(2)15-11-25-21(27-19(15)26-20(22)30)29-18-8-7-13(23)10-14(18)17(28-29)9-12-5-3-4-6-16(12)24/h3-8,10-11H,9H2,1-2H3,(H,25,26,27,30)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
n/an/a 400n/an/an/an/a7.5n/a



Bayer Intellectual Property GmbH

US Patent


Assay Description
To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...

US Patent US9023849 (2015)


BindingDB Entry DOI: 10.7270/Q2TD9W3Q
More data for this
Ligand-Target Pair