null

SMILES: CC1(C)C(=O)Nc2nc(ncc12)-c1nn(Cc2ccccc2F)c2CCCc12

InChI Key: InChIKey=WIJJOWCTDWQEGE-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 157143   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM157143 (US9023849, 11) Show SMILES CC1(C)C(=O)Nc2nc(ncc12)-c1nn(Cc2ccccc2F)c2CCCc12 Show InChI InChI=1S/C21H20FN5O/c1-21(2)14-10-23-19(24-18(14)25-20(21)28)17-13-7-5-9-16(13)27(26-17)11-12-6-3-4-8-15(12)22/h3-4,6,8,10H,5,7,9,11H2,1-2H3,(H,23,24,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Intellectual Property GmbH US Patent					Assay Description To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...				US Patent US9023849 (2015) BindingDB Entry DOI: 10.7270/Q2TD9W3Q
					More data for this Ligand-Target Pair