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SMILES: CCCc1nc(nc2NC(=O)C(C)(C)c12)-n1nc(Cc2ccccc2F)c2ccccc12

InChI Key: InChIKey=YSFPRKWYBHJEAB-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 157157   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM157157 (US9023849, 28) Show SMILES CCCc1nc(nc2NC(=O)C(C)(C)c12)-n1nc(Cc2ccccc2F)c2ccccc12 Show InChI InChI=1S/C25H24FN5O/c1-4-9-18-21-22(28-23(32)25(21,2)3)29-24(27-18)31-20-13-8-6-11-16(20)19(30-31)14-15-10-5-7-12-17(15)26/h5-8,10-13H,4,9,14H2,1-3H3,(H,27,28,29,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	450	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Intellectual Property GmbH US Patent					Assay Description To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...				US Patent US9023849 (2015) BindingDB Entry DOI: 10.7270/Q2TD9W3Q
					More data for this Ligand-Target Pair