BDBM15757 3-(4-Fluorophenyl)-2-pyridin-4-yl)-1H-pyrrolo[3,2-c]-pyridine::4-[3-(4-fluorophenyl)-1H-pyrrolo[3,2-c]pyridin-2-yl]pyridine::5-Azaindole 15

SMILES: Fc1ccc(cc1)-c1c([nH]c2ccncc12)-c1ccncc1

InChI Key: InChIKey=VUSIVTWEFRVZIG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15757   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15757 (3-(4-Fluorophenyl)-2-pyridin-4-yl)-1H-pyrrolo[3,2-...) Show SMILES Fc1ccc(cc1)-c1c([nH]c2ccncc12)-c1ccncc1 Show InChI InChI=1S/C18H12FN3/c19-14-3-1-12(2-4-14)17-15-11-21-10-7-16(15)22-18(17)13-5-8-20-9-6-13/h1-11,22H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	7.4	30
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 46: 4702-13 (2003) Article DOI: 10.1021/jm0301787 BindingDB Entry DOI: 10.7270/Q2ZG6QHT
					More data for this Ligand-Target Pair