null
SMILES: CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CO)C(O)=O
InChI Key: InChIKey=LFSLIAZOFSRRDB-HNNXBMFYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Enteropeptidase (Homo sapiens (Human)) | BDBM158083 (US9024044, 11 | US9227949, 11) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.410 | n/a | n/a | n/a | n/a | n/a | n/a | 8.0 | n/a |
Ajinomoto Co., Inc. US Patent | Assay Description Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su... | US Patent US9024044 (2015) BindingDB Entry DOI: 10.7270/Q2F47MVB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Homo sapiens (Human)) | BDBM158083 (US9024044, 11 | US9227949, 11) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 1.87 | n/a | n/a | n/a | n/a | n/a | n/a | 8.0 | n/a |
AJINOMOTO CO., INC. US Patent | Assay Description Using a 96 well plate (#3915, Costar), a test compound (25 uL) was mixed with 20 uM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 uL) mixed ... | US Patent US9227949 (2016) BindingDB Entry DOI: 10.7270/Q2959GBT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Enteropeptidase (Homo sapiens (Human)) | BDBM158083 (US9024044, 11 | US9227949, 11) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.410 | n/a | n/a | n/a | n/a | n/a | n/a | 8.0 | n/a |
AJINOMOTO CO., INC. US Patent | Assay Description Using a 96 well plate (#3915, Costar), a test compound (25 uL), 400 mM Tris-HCl buffer (pH 8.0, 25 uL) and 0.5 mg/mL, fluorescence enzyme substrate (... | US Patent US9227949 (2016) BindingDB Entry DOI: 10.7270/Q2959GBT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Homo sapiens (Human)) | BDBM158083 (US9024044, 11 | US9227949, 11) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 1.87 | n/a | n/a | n/a | n/a | n/a | n/a | 8.0 | n/a |
Ajinomoto Co., Inc. US Patent | Assay Description Using a 96 well plate (#3915, Costar), a test compound (25 μL) was mixed with 20 μM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 ... | US Patent US9024044 (2015) BindingDB Entry DOI: 10.7270/Q2F47MVB | |||||||||||
More data for this Ligand-Target Pair |