null

SMILES: OC(=O)c1cc(Br)ccc1C(=O)Nc1cccnc1

InChI Key: InChIKey=GAFVBLKKCZBSJZ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 159162   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sortilin (Homo sapiens (Human))	BDBM159162 (US10195186, Example 26 | US9682967, 26) Show SMILES OC(=O)c1cc(Br)ccc1C(=O)Nc1cccnc1 Show InChI InChI=1S/C13H9BrN2O3/c14-8-3-4-10(11(6-8)13(18)19)12(17)16-9-2-1-5-15-7-9/h1-7H,(H,16,17)(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.24E+3	n/a	5.50E+3	n/a	n/a	n/a	n/a	7.4	n/a
H. Lundbeck A/S US Patent					Assay Description The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...				US Patent US9682967 (2017) BindingDB Entry DOI: 10.7270/Q22805SC
					More data for this Ligand-Target Pair
Sortilin (Homo sapiens (Human))	BDBM159162 (US10195186, Example 26 | US9682967, 26) Show SMILES OC(=O)c1cc(Br)ccc1C(=O)Nc1cccnc1 Show InChI InChI=1S/C13H9BrN2O3/c14-8-3-4-10(11(6-8)13(18)19)12(17)16-9-2-1-5-15-7-9/h1-7H,(H,16,17)(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.24E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S US Patent					Assay Description The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...				US Patent US10195186 (2019) BindingDB Entry DOI: 10.7270/Q2474CZW
					More data for this Ligand-Target Pair
Sortilin (Homo sapiens (Human))	BDBM159162 (US10195186, Example 26 | US9682967, 26) Show SMILES OC(=O)c1cc(Br)ccc1C(=O)Nc1cccnc1 Show InChI InChI=1S/C13H9BrN2O3/c14-8-3-4-10(11(6-8)13(18)19)12(17)16-9-2-1-5-15-7-9/h1-7H,(H,16,17)(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S US Patent					Assay Description The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...				US Patent US10195186 (2019) BindingDB Entry DOI: 10.7270/Q2474CZW
					More data for this Ligand-Target Pair