null
SMILES: FC(F)(F)c1ccc(nn1)-c1ccc2C(CCNc2c1)c1ccc(Cl)cc1
InChI Key: InChIKey=ILPGXQBGCYEMTR-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM159325 (US9034899, 4 | US9604960, 4) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 21.4 | n/a | n/a | n/a | n/a | 7.5 | 4 |
Albany Molecular Research, Inc. US Patent | Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0.... | US Patent US9034899 (2015) BindingDB Entry DOI: 10.7270/Q20000VT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Homo sapiens (Human)) | BDBM159325 (US9034899, 4 | US9604960, 4) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 138 | n/a | n/a | n/a | n/a | 7.9 | 4 |
Albany Molecular Research, Inc. US Patent | Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0.... | US Patent US9034899 (2015) BindingDB Entry DOI: 10.7270/Q20000VT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent noradrenaline transporter (Homo sapiens (Human)) | BDBM159325 (US9034899, 4 | US9604960, 4) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 47 | n/a | n/a | n/a | n/a | n/a | n/a |
Albany Molecular Research, Inc. US Patent | Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 1.... | US Patent US9604960 (2017) BindingDB Entry DOI: 10.7270/Q2QC05KM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM159325 (US9034899, 4 | US9604960, 4) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Albany Molecular Research, Inc. US Patent | Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0.... | US Patent US9604960 (2017) BindingDB Entry DOI: 10.7270/Q2QC05KM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Homo sapiens (Human)) | BDBM159325 (US9034899, 4 | US9604960, 4) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 138 | n/a | n/a | n/a | n/a | n/a | n/a |
Albany Molecular Research, Inc. US Patent | Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0.... | US Patent US9604960 (2017) BindingDB Entry DOI: 10.7270/Q2QC05KM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent noradrenaline transporter (Homo sapiens (Human)) | BDBM159325 (US9034899, 4 | US9604960, 4) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 47.3 | n/a | n/a | n/a | n/a | 7.5 | 4 |
Albany Molecular Research, Inc. US Patent | Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 1.... | US Patent US9034899 (2015) BindingDB Entry DOI: 10.7270/Q20000VT | |||||||||||
More data for this Ligand-Target Pair |