BDBM159332 US9034899, 15::US9604960, 15

SMILES: Clc1ccc(cc1Cl)C1CNCc2cc(ccc12)-c1cccc(c1)C#N

InChI Key: InChIKey=ZWAMWGRVKGXYIC-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 159332   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM159332 (US9034899, 15 | US9604960, 15) Show SMILES Clc1ccc(cc1Cl)C1CNCc2cc(ccc12)-c1cccc(c1)C#N Show InChI InChI=1S/C22H16Cl2N2/c23-21-7-5-17(10-22(21)24)20-13-26-12-18-9-16(4-6-19(18)20)15-3-1-2-14(8-15)11-25/h1-10,20,26H,12-13H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	7.5	4
Albany Molecular Research, Inc. US Patent					Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0....				US Patent US9034899 (2015) BindingDB Entry DOI: 10.7270/Q20000VT
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM159332 (US9034899, 15 | US9604960, 15) Show SMILES Clc1ccc(cc1Cl)C1CNCc2cc(ccc12)-c1cccc(c1)C#N Show InChI InChI=1S/C22H16Cl2N2/c23-21-7-5-17(10-22(21)24)20-13-26-12-18-9-16(4-6-19(18)20)15-3-1-2-14(8-15)11-25/h1-10,20,26H,12-13H2	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	213	n/a	n/a	n/a	n/a	7.9	4
Albany Molecular Research, Inc. US Patent					Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0....				US Patent US9034899 (2015) BindingDB Entry DOI: 10.7270/Q20000VT
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM159332 (US9034899, 15 | US9604960, 15) Show SMILES Clc1ccc(cc1Cl)C1CNCc2cc(ccc12)-c1cccc(c1)C#N Show InChI InChI=1S/C22H16Cl2N2/c23-21-7-5-17(10-22(21)24)20-13-26-12-18-9-16(4-6-19(18)20)15-3-1-2-14(8-15)11-25/h1-10,20,26H,12-13H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	86	n/a	n/a	n/a	n/a	n/a	n/a
Albany Molecular Research, Inc. US Patent					Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 1....				US Patent US9604960 (2017) BindingDB Entry DOI: 10.7270/Q2QC05KM
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM159332 (US9034899, 15 | US9604960, 15) Show SMILES Clc1ccc(cc1Cl)C1CNCc2cc(ccc12)-c1cccc(c1)C#N Show InChI InChI=1S/C22H16Cl2N2/c23-21-7-5-17(10-22(21)24)20-13-26-12-18-9-16(4-6-19(18)20)15-3-1-2-14(8-15)11-25/h1-10,20,26H,12-13H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Albany Molecular Research, Inc. US Patent					Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0....				US Patent US9604960 (2017) BindingDB Entry DOI: 10.7270/Q2QC05KM
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM159332 (US9034899, 15 | US9604960, 15) Show SMILES Clc1ccc(cc1Cl)C1CNCc2cc(ccc12)-c1cccc(c1)C#N Show InChI InChI=1S/C22H16Cl2N2/c23-21-7-5-17(10-22(21)24)20-13-26-12-18-9-16(4-6-19(18)20)15-3-1-2-14(8-15)11-25/h1-10,20,26H,12-13H2	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	213	n/a	n/a	n/a	n/a	n/a	n/a
Albany Molecular Research, Inc. US Patent					Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0....				US Patent US9604960 (2017) BindingDB Entry DOI: 10.7270/Q2QC05KM
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM159332 (US9034899, 15 | US9604960, 15) Show SMILES Clc1ccc(cc1Cl)C1CNCc2cc(ccc12)-c1cccc(c1)C#N Show InChI InChI=1S/C22H16Cl2N2/c23-21-7-5-17(10-22(21)24)20-13-26-12-18-9-16(4-6-19(18)20)15-3-1-2-14(8-15)11-25/h1-10,20,26H,12-13H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	86	n/a	n/a	n/a	n/a	7.5	4
Albany Molecular Research, Inc. US Patent					Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 1....				US Patent US9034899 (2015) BindingDB Entry DOI: 10.7270/Q20000VT
					More data for this Ligand-Target Pair