null

SMILES: CS(=O)(=O)c1ccc(cc1)-c1ccc2C(CNCc2c1)c1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=MFFCMNOKOQHLPH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 159333   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM159333 (US9034899, 16 | US9604960, 16) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1ccc2C(CNCc2c1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C22H19Cl2NO2S/c1-28(26,27)18-6-2-14(3-7-18)15-4-8-19-17(10-15)12-25-13-20(19)16-5-9-21(23)22(24)11-16/h2-11,20,25H,12-13H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	7.5	4
Albany Molecular Research, Inc. US Patent					Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0....				US Patent US9034899 (2015) BindingDB Entry DOI: 10.7270/Q20000VT
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM159333 (US9034899, 16 | US9604960, 16) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1ccc2C(CNCc2c1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C22H19Cl2NO2S/c1-28(26,27)18-6-2-14(3-7-18)15-4-8-19-17(10-15)12-25-13-20(19)16-5-9-21(23)22(24)11-16/h2-11,20,25H,12-13H2,1H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	77	n/a	n/a	n/a	n/a	7.9	4
Albany Molecular Research, Inc. US Patent					Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0....				US Patent US9034899 (2015) BindingDB Entry DOI: 10.7270/Q20000VT
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM159333 (US9034899, 16 | US9604960, 16) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1ccc2C(CNCc2c1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C22H19Cl2NO2S/c1-28(26,27)18-6-2-14(3-7-18)15-4-8-19-17(10-15)12-25-13-20(19)16-5-9-21(23)22(24)11-16/h2-11,20,25H,12-13H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Albany Molecular Research, Inc. US Patent					Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 1....				US Patent US9604960 (2017) BindingDB Entry DOI: 10.7270/Q2QC05KM
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM159333 (US9034899, 16 | US9604960, 16) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1ccc2C(CNCc2c1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C22H19Cl2NO2S/c1-28(26,27)18-6-2-14(3-7-18)15-4-8-19-17(10-15)12-25-13-20(19)16-5-9-21(23)22(24)11-16/h2-11,20,25H,12-13H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Albany Molecular Research, Inc. US Patent					Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0....				US Patent US9604960 (2017) BindingDB Entry DOI: 10.7270/Q2QC05KM
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM159333 (US9034899, 16 | US9604960, 16) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1ccc2C(CNCc2c1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C22H19Cl2NO2S/c1-28(26,27)18-6-2-14(3-7-18)15-4-8-19-17(10-15)12-25-13-20(19)16-5-9-21(23)22(24)11-16/h2-11,20,25H,12-13H2,1H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
Albany Molecular Research, Inc. US Patent					Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0....				US Patent US9604960 (2017) BindingDB Entry DOI: 10.7270/Q2QC05KM
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM159333 (US9034899, 16 | US9604960, 16) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1ccc2C(CNCc2c1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C22H19Cl2NO2S/c1-28(26,27)18-6-2-14(3-7-18)15-4-8-19-17(10-15)12-25-13-20(19)16-5-9-21(23)22(24)11-16/h2-11,20,25H,12-13H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	7.5	4
Albany Molecular Research, Inc. US Patent					Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 1....				US Patent US9034899 (2015) BindingDB Entry DOI: 10.7270/Q20000VT
					More data for this Ligand-Target Pair