BDBM159334 US9034899, 17::US9604960, 17

SMILES: Clc1ccc(cc1Cl)C1CNCc2cc(ccc12)-n1ccccc1=O

InChI Key: InChIKey=PILUFBWYZBSMTQ-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 159334   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM159334 (US9034899, 17 | US9604960, 17) Show SMILES Clc1ccc(cc1Cl)C1CNCc2cc(ccc12)-n1ccccc1=O Show InChI InChI=1S/C20H16Cl2N2O/c21-18-7-4-13(10-19(18)22)17-12-23-11-14-9-15(5-6-16(14)17)24-8-2-1-3-20(24)25/h1-10,17,23H,11-12H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.90	n/a	n/a	n/a	n/a	7.5	4
Albany Molecular Research, Inc. US Patent					Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0....				US Patent US9034899 (2015) BindingDB Entry DOI: 10.7270/Q20000VT
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM159334 (US9034899, 17 | US9604960, 17) Show SMILES Clc1ccc(cc1Cl)C1CNCc2cc(ccc12)-n1ccccc1=O Show InChI InChI=1S/C20H16Cl2N2O/c21-18-7-4-13(10-19(18)22)17-12-23-11-14-9-15(5-6-16(14)17)24-8-2-1-3-20(24)25/h1-10,17,23H,11-12H2	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	84.7	n/a	n/a	n/a	n/a	7.9	4
Albany Molecular Research, Inc. US Patent					Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0....				US Patent US9034899 (2015) BindingDB Entry DOI: 10.7270/Q20000VT
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM159334 (US9034899, 17 | US9604960, 17) Show SMILES Clc1ccc(cc1Cl)C1CNCc2cc(ccc12)-n1ccccc1=O Show InChI InChI=1S/C20H16Cl2N2O/c21-18-7-4-13(10-19(18)22)17-12-23-11-14-9-15(5-6-16(14)17)24-8-2-1-3-20(24)25/h1-10,17,23H,11-12H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	421	n/a	n/a	n/a	n/a	n/a	n/a
Albany Molecular Research, Inc. US Patent					Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 1....				US Patent US9604960 (2017) BindingDB Entry DOI: 10.7270/Q2QC05KM
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM159334 (US9034899, 17 | US9604960, 17) Show SMILES Clc1ccc(cc1Cl)C1CNCc2cc(ccc12)-n1ccccc1=O Show InChI InChI=1S/C20H16Cl2N2O/c21-18-7-4-13(10-19(18)22)17-12-23-11-14-9-15(5-6-16(14)17)24-8-2-1-3-20(24)25/h1-10,17,23H,11-12H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.90	n/a	n/a	n/a	n/a	n/a	n/a
Albany Molecular Research, Inc. US Patent					Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0....				US Patent US9604960 (2017) BindingDB Entry DOI: 10.7270/Q2QC05KM
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM159334 (US9034899, 17 | US9604960, 17) Show SMILES Clc1ccc(cc1Cl)C1CNCc2cc(ccc12)-n1ccccc1=O Show InChI InChI=1S/C20H16Cl2N2O/c21-18-7-4-13(10-19(18)22)17-12-23-11-14-9-15(5-6-16(14)17)24-8-2-1-3-20(24)25/h1-10,17,23H,11-12H2	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	n/a
Albany Molecular Research, Inc. US Patent					Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0....				US Patent US9604960 (2017) BindingDB Entry DOI: 10.7270/Q2QC05KM
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM159334 (US9034899, 17 | US9604960, 17) Show SMILES Clc1ccc(cc1Cl)C1CNCc2cc(ccc12)-n1ccccc1=O Show InChI InChI=1S/C20H16Cl2N2O/c21-18-7-4-13(10-19(18)22)17-12-23-11-14-9-15(5-6-16(14)17)24-8-2-1-3-20(24)25/h1-10,17,23H,11-12H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	421	n/a	n/a	n/a	n/a	7.5	4
Albany Molecular Research, Inc. US Patent					Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 1....				US Patent US9034899 (2015) BindingDB Entry DOI: 10.7270/Q20000VT
					More data for this Ligand-Target Pair