BDBM159339 US9034899, 29::US9604960, 29
SMILES: Fc1cc2C(CNCc2cc1-c1ccc(nn1)C(F)(F)F)c1ccc(Cl)c(Cl)c1
InChI Key: InChIKey=NIXMEJRSHLSZKN-UHFFFAOYSA-N
Data: 6 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM159339 (US9034899, 29 | US9604960, 29) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 29.7 | n/a | n/a | n/a | n/a | 7.5 | 4 |
Albany Molecular Research, Inc. US Patent | Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0.... | US Patent US9034899 (2015) BindingDB Entry DOI: 10.7270/Q20000VT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Homo sapiens (Human)) | BDBM159339 (US9034899, 29 | US9604960, 29) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 78.3 | n/a | n/a | n/a | n/a | 7.9 | 4 |
Albany Molecular Research, Inc. US Patent | Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0.... | US Patent US9034899 (2015) BindingDB Entry DOI: 10.7270/Q20000VT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent noradrenaline transporter (Homo sapiens (Human)) | BDBM159339 (US9034899, 29 | US9604960, 29) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
Albany Molecular Research, Inc. US Patent | Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 1.... | US Patent US9604960 (2017) BindingDB Entry DOI: 10.7270/Q2QC05KM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM159339 (US9034899, 29 | US9604960, 29) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Albany Molecular Research, Inc. US Patent | Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0.... | US Patent US9604960 (2017) BindingDB Entry DOI: 10.7270/Q2QC05KM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Homo sapiens (Human)) | BDBM159339 (US9034899, 29 | US9604960, 29) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 78 | n/a | n/a | n/a | n/a | n/a | n/a |
Albany Molecular Research, Inc. US Patent | Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0.... | US Patent US9604960 (2017) BindingDB Entry DOI: 10.7270/Q2QC05KM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent noradrenaline transporter (Homo sapiens (Human)) | BDBM159339 (US9034899, 29 | US9604960, 29) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 34.1 | n/a | n/a | n/a | n/a | 7.5 | 4 |
Albany Molecular Research, Inc. US Patent | Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 1.... | US Patent US9034899 (2015) BindingDB Entry DOI: 10.7270/Q20000VT | |||||||||||
More data for this Ligand-Target Pair |