BDBM159343 US9034899, 34::US9604960, 34

SMILES: Nc1ccc(nn1)-c1ccc2C(CNCc2c1)c1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=ZNELUNAFGGGGOF-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 159343   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM159343 (US9034899, 34 | US9604960, 34) Show SMILES Nc1ccc(nn1)-c1ccc2C(CNCc2c1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C19H16Cl2N4/c20-16-4-2-11(8-17(16)21)15-10-23-9-13-7-12(1-3-14(13)15)18-5-6-19(22)25-24-18/h1-8,15,23H,9-10H2,(H2,22,25)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.80	n/a	n/a	n/a	n/a	7.5	4
Albany Molecular Research, Inc. US Patent					Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0....				US Patent US9034899 (2015) BindingDB Entry DOI: 10.7270/Q20000VT
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM159343 (US9034899, 34 | US9604960, 34) Show SMILES Nc1ccc(nn1)-c1ccc2C(CNCc2c1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C19H16Cl2N4/c20-16-4-2-11(8-17(16)21)15-10-23-9-13-7-12(1-3-14(13)15)18-5-6-19(22)25-24-18/h1-8,15,23H,9-10H2,(H2,22,25)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7.10	n/a	n/a	n/a	n/a	7.9	4
Albany Molecular Research, Inc. US Patent					Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0....				US Patent US9034899 (2015) BindingDB Entry DOI: 10.7270/Q20000VT
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM159343 (US9034899, 34 | US9604960, 34) Show SMILES Nc1ccc(nn1)-c1ccc2C(CNCc2c1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C19H16Cl2N4/c20-16-4-2-11(8-17(16)21)15-10-23-9-13-7-12(1-3-14(13)15)18-5-6-19(22)25-24-18/h1-8,15,23H,9-10H2,(H2,22,25)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Albany Molecular Research, Inc. US Patent					Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 1....				US Patent US9604960 (2017) BindingDB Entry DOI: 10.7270/Q2QC05KM
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM159343 (US9034899, 34 | US9604960, 34) Show SMILES Nc1ccc(nn1)-c1ccc2C(CNCc2c1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C19H16Cl2N4/c20-16-4-2-11(8-17(16)21)15-10-23-9-13-7-12(1-3-14(13)15)18-5-6-19(22)25-24-18/h1-8,15,23H,9-10H2,(H2,22,25)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Albany Molecular Research, Inc. US Patent					Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0....				US Patent US9604960 (2017) BindingDB Entry DOI: 10.7270/Q2QC05KM
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM159343 (US9034899, 34 | US9604960, 34) Show SMILES Nc1ccc(nn1)-c1ccc2C(CNCc2c1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C19H16Cl2N4/c20-16-4-2-11(8-17(16)21)15-10-23-9-13-7-12(1-3-14(13)15)18-5-6-19(22)25-24-18/h1-8,15,23H,9-10H2,(H2,22,25)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7.10	n/a	n/a	n/a	n/a	n/a	n/a
Albany Molecular Research, Inc. US Patent					Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0....				US Patent US9604960 (2017) BindingDB Entry DOI: 10.7270/Q2QC05KM
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM159343 (US9034899, 34 | US9604960, 34) Show SMILES Nc1ccc(nn1)-c1ccc2C(CNCc2c1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C19H16Cl2N4/c20-16-4-2-11(8-17(16)21)15-10-23-9-13-7-12(1-3-14(13)15)18-5-6-19(22)25-24-18/h1-8,15,23H,9-10H2,(H2,22,25)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	22.9	n/a	n/a	n/a	n/a	7.5	4
Albany Molecular Research, Inc. US Patent					Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 1....				US Patent US9034899 (2015) BindingDB Entry DOI: 10.7270/Q20000VT
					More data for this Ligand-Target Pair