BDBM159345 US9034899, 36::US9173879, 1 (-) - enantiomer::US9604960, 36
SMILES: Clc1ccc(cc1Cl)C1CNCc2cc(ccc12)-c1ccc2ncnn2c1
InChI Key: InChIKey=VXVOMCCQHIVMJK-UHFFFAOYSA-N
Data: 12 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM159345 (US9034899, 36 | US9173879, 1 (-) - enantiomer | US...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | 7.5 | 4 |
Albany Molecular Research, Inc. US Patent | Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0.... | US Patent US9034899 (2015) BindingDB Entry DOI: 10.7270/Q20000VT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Homo sapiens (Human)) | BDBM159345 (US9034899, 36 | US9173879, 1 (-) - enantiomer | US...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 30.8 | n/a | n/a | n/a | n/a | 7.9 | 4 |
Albany Molecular Research, Inc. US Patent | Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0.... | US Patent US9034899 (2015) BindingDB Entry DOI: 10.7270/Q20000VT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent noradrenaline transporter (Homo sapiens (Human)) | BDBM159345 (US9034899, 36 | US9173879, 1 (-) - enantiomer | US...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 26 | n/a | n/a | n/a | n/a | 7.5 | 4 |
Albany Molecular Research, Inc. US Patent | Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 1.... | US Patent US9034899 (2015) BindingDB Entry DOI: 10.7270/Q20000VT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM159345 (US9034899, 36 | US9173879, 1 (-) - enantiomer | US...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0.... | US Patent US9173879 (2015) BindingDB Entry DOI: 10.7270/Q2T72G75 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM159345 (US9034899, 36 | US9173879, 1 (-) - enantiomer | US...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 4.20 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0.... | US Patent US9173879 (2015) BindingDB Entry DOI: 10.7270/Q2T72G75 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent noradrenaline transporter (Homo sapiens (Human)) | BDBM159345 (US9034899, 36 | US9173879, 1 (-) - enantiomer | US...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Albany Molecular Research, Inc. US Patent | Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 1.... | US Patent US9604960 (2017) BindingDB Entry DOI: 10.7270/Q2QC05KM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Homo sapiens (Human)) | BDBM159345 (US9034899, 36 | US9173879, 1 (-) - enantiomer | US...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 105 | n/a | n/a | n/a | n/a | 7.5 | 4 |
Bristol-Myers Squibb Company US Patent | Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0.... | US Patent US9173879 (2015) BindingDB Entry DOI: 10.7270/Q2T72G75 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent noradrenaline transporter (Homo sapiens (Human)) | BDBM159345 (US9034899, 36 | US9173879, 1 (-) - enantiomer | US...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 26 | n/a | n/a | n/a | n/a | 7.5 | 4 |
Bristol-Myers Squibb Company US Patent | Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 1.... | US Patent US9173879 (2015) BindingDB Entry DOI: 10.7270/Q2T72G75 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent noradrenaline transporter (Homo sapiens (Human)) | BDBM159345 (US9034899, 36 | US9173879, 1 (-) - enantiomer | US...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 4.80 | n/a | n/a | n/a | n/a | 7.5 | 4 |
Bristol-Myers Squibb Company US Patent | Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 1.... | US Patent US9173879 (2015) BindingDB Entry DOI: 10.7270/Q2T72G75 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM159345 (US9034899, 36 | US9173879, 1 (-) - enantiomer | US...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Albany Molecular Research, Inc. US Patent | Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0.... | US Patent US9604960 (2017) BindingDB Entry DOI: 10.7270/Q2QC05KM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Homo sapiens (Human)) | BDBM159345 (US9034899, 36 | US9173879, 1 (-) - enantiomer | US...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
Albany Molecular Research, Inc. US Patent | Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0.... | US Patent US9604960 (2017) BindingDB Entry DOI: 10.7270/Q2QC05KM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Homo sapiens (Human)) | BDBM159345 (US9034899, 36 | US9173879, 1 (-) - enantiomer | US...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 30.8 | n/a | n/a | n/a | n/a | 7.5 | 4 |
Bristol-Myers Squibb Company US Patent | Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0.... | US Patent US9173879 (2015) BindingDB Entry DOI: 10.7270/Q2T72G75 | |||||||||||
More data for this Ligand-Target Pair |