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SMILES: Cc1cc(cc(F)c1CO)-c1cc(C2CCCNC2)n2ncnc(N)c12

InChI Key: InChIKey=YXBKQVQHUYJBEU-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 160303   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine/threonine-protein kinase receptor R3


(Homo sapiens (Human))		BDBM160303
PNG
(US9040691, 31)
Show SMILES Cc1cc(cc(F)c1CO)-c1cc(C2CCCNC2)n2ncnc(N)c12
Show InChI InChI=1S/C19H22FN5O/c1-11-5-13(6-16(20)15(11)9-26)14-7-17(12-3-2-4-22-8-12)25-18(14)19(21)23-10-24-25/h5-7,10,12,22,26H,2-4,8-9H2,1H3,(H2,21,23,24)
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Similars
US Patent
n/an/a 4n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...

US Patent US9040691 (2015)


BindingDB Entry DOI: 10.7270/Q25H7F1T
More data for this
Ligand-Target Pair