BDBM161025 US9108905, 14

SMILES: CC\C(=N/O)\C(\C)=C\c1ccc(F)c(F)c1

InChI Key: InChIKey=WRDLKTQRPOZITC-QWPOMPHKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 161025   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM161025 (US9108905, 14) Show SMILES CC\C(=N/O)\C(\C)=C\c1ccc(F)c(F)c1 Show InChI InChI=1S/C12H13F2NO/c1-3-12(15-16)8(2)6-9-4-5-10(13)11(14)7-9/h4-7,16H,3H2,1-2H3/b8-6+,15-12+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	574	n/a	n/a	n/a	n/a	n/a	25
AbbVie Inc. US Patent					Assay Description Ca2+ influx was measured using a FLIPR calcium assay kit (R8033; Molecular Devices, Sunnyvale, Calif.). The Ca2+ indicator dye was dissolved in Hanks...				US Patent US9108905 (2015) BindingDB Entry DOI: 10.7270/Q2ZS2V7G
					More data for this Ligand-Target Pair