BDBM161033 US9108947, 3
SMILES: Cc1c2COC(=O)c2ccc1[C@@H](O)CNCC1CCCN1C[C@H](O)c1ccc2C(=O)OCc2c1C
InChI Key: InChIKey=XILVOFIUCIPGKQ-GSIQFNFPSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ATP-sensitive inward rectifier potassium channel 1 (Homo sapiens (Human)) | BDBM161033 (US9108947, 3) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 510 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Merck Sharp & Dohme Corp. US Patent | Assay Description Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks.RT... | US Patent US9108947 (2015) BindingDB Entry DOI: 10.7270/Q2V40SZT | |||||||||||
More data for this Ligand-Target Pair |