BDBM161956 US9682991, 11

SMILES: CCN1CCOc2c1c(NCC1CC1)nn1c(nnc21)-c1cccc(OC(F)(F)F)c1

InChI Key: InChIKey=GGNCDVGJGYTHOR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 161956   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM161956 (US9682991, 11) Show SMILES CCN1CCOc2c1c(NCC1CC1)nn1c(nnc21)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C20H21F3N6O2/c1-2-28-8-9-30-16-15(28)17(24-11-12-6-7-12)27-29-18(25-26-19(16)29)13-4-3-5-14(10-13)31-20(21,22)23/h3-5,10,12H,2,6-9,11H2,1H3,(H,24,27)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-2 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM161956 (US9682991, 11) Show SMILES CCN1CCOc2c1c(NCC1CC1)nn1c(nnc21)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C20H21F3N6O2/c1-2-28-8-9-30-16-15(28)17(24-11-12-6-7-12)27-29-18(25-26-19(16)29)13-4-3-5-14(10-13)31-20(21,22)23/h3-5,10,12H,2,6-9,11H2,1H3,(H,24,27)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-1 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair