BDBM161968 US9682991, 17

SMILES: CN1CCC(CNc2nn3c(nnc3c3N(C)CCOc23)-c2cccc(OC(F)(F)F)c2)CC1

InChI Key: InChIKey=CJJQJGCGAHFGLB-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 161968   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM161968 (US9682991, 17) Show SMILES CN1CCC(CNc2nn3c(nnc3c3N(C)CCOc23)-c2cccc(OC(F)(F)F)c2)CC1 Show InChI InChI=1S/C22H26F3N7O2/c1-30-8-6-14(7-9-30)13-26-19-18-17(31(2)10-11-33-18)21-28-27-20(32(21)29-19)15-4-3-5-16(12-15)34-22(23,24)25/h3-5,12,14H,6-11,13H2,1-2H3,(H,26,29)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-1 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM161968 (US9682991, 17) Show SMILES CN1CCC(CNc2nn3c(nnc3c3N(C)CCOc23)-c2cccc(OC(F)(F)F)c2)CC1 Show InChI InChI=1S/C22H26F3N7O2/c1-30-8-6-14(7-9-30)13-26-19-18-17(31(2)10-11-33-18)21-28-27-20(32(21)29-19)15-4-3-5-16(12-15)34-22(23,24)25/h3-5,12,14H,6-11,13H2,1-2H3,(H,26,29)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-3 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM161968 (US9682991, 17) Show SMILES CN1CCC(CNc2nn3c(nnc3c3N(C)CCOc23)-c2cccc(OC(F)(F)F)c2)CC1 Show InChI InChI=1S/C22H26F3N7O2/c1-30-8-6-14(7-9-30)13-26-19-18-17(31(2)10-11-33-18)21-28-27-20(32(21)29-19)15-4-3-5-16(12-15)34-22(23,24)25/h3-5,12,14H,6-11,13H2,1-2H3,(H,26,29)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-2 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair