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SMILES: CN1CCN(CCNc2nn3c(nnc3c3OCCN(C)c23)-c2cccc(OC(F)(F)F)c2)CC1

InChI Key: InChIKey=SBHBCLQNJOIBQN-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 161978   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM161978 (US9682991, 27) Show SMILES CN1CCN(CCNc2nn3c(nnc3c3OCCN(C)c23)-c2cccc(OC(F)(F)F)c2)CC1 Show InChI InChI=1S/C22H27F3N8O2/c1-30-8-10-32(11-9-30)7-6-26-19-17-18(34-13-12-31(17)2)21-28-27-20(33(21)29-19)15-4-3-5-16(14-15)35-22(23,24)25/h3-5,14H,6-13H2,1-2H3,(H,26,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-1 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM161978 (US9682991, 27) Show SMILES CN1CCN(CCNc2nn3c(nnc3c3OCCN(C)c23)-c2cccc(OC(F)(F)F)c2)CC1 Show InChI InChI=1S/C22H27F3N8O2/c1-30-8-10-32(11-9-30)7-6-26-19-17-18(34-13-12-31(17)2)21-28-27-20(33(21)29-19)15-4-3-5-16(14-15)35-22(23,24)25/h3-5,14H,6-13H2,1-2H3,(H,26,29)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-3 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM161978 (US9682991, 27) Show SMILES CN1CCN(CCNc2nn3c(nnc3c3OCCN(C)c23)-c2cccc(OC(F)(F)F)c2)CC1 Show InChI InChI=1S/C22H27F3N8O2/c1-30-8-10-32(11-9-30)7-6-26-19-17-18(34-13-12-31(17)2)21-28-27-20(33(21)29-19)15-4-3-5-16(14-15)35-22(23,24)25/h3-5,14H,6-13H2,1-2H3,(H,26,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-2 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair