BDBM161993 US9682991, 42

SMILES: CN1CCOc2c(NCCN3CCNCC3)nn3c(nnc3c12)-c1cccc(OC(F)(F)F)c1

InChI Key: InChIKey=GBWWJRWDGHFURK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 161993   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM161993 (US9682991, 42) Show SMILES CN1CCOc2c(NCCN3CCNCC3)nn3c(nnc3c12)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C21H25F3N8O2/c1-30-11-12-33-17-16(30)20-28-27-19(14-3-2-4-15(13-14)34-21(22,23)24)32(20)29-18(17)26-7-10-31-8-5-25-6-9-31/h2-4,13,25H,5-12H2,1H3,(H,26,29)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-2 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM161993 (US9682991, 42) Show SMILES CN1CCOc2c(NCCN3CCNCC3)nn3c(nnc3c12)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C21H25F3N8O2/c1-30-11-12-33-17-16(30)20-28-27-19(14-3-2-4-15(13-14)34-21(22,23)24)32(20)29-18(17)26-7-10-31-8-5-25-6-9-31/h2-4,13,25H,5-12H2,1H3,(H,26,29)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-1 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair