BDBM16387 4-{6-[4-(4-fluorophenyl)-1,3-oxazol-5-yl]-[1,2,4]triazolo[3,4-a]pyridin-3-yl}morpholine::triazolopyridine oxazole inhibitor 58

SMILES: Fc1ccc(cc1)-c1ncoc1-c1ccc2nnc(N3CCOCC3)n2c1

InChI Key: InChIKey=LMYKNINLHCJDHE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 16387   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM16387 (4-{6-[4-(4-fluorophenyl)-1,3-oxazol-5-yl]-[1,2,4]t...) Show SMILES Fc1ccc(cc1)-c1ncoc1-c1ccc2nnc(N3CCOCC3)n2c1 Show InChI InChI=1S/C19H16FN5O2/c20-15-4-1-13(2-5-15)17-18(27-12-21-17)14-3-6-16-22-23-19(25(16)11-14)24-7-9-26-10-8-24/h1-6,11-12H,7-10H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11.8	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...				Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ
					More data for this Ligand-Target Pair