BDBM164228 US9688615, 39
SMILES: NCC(=O)NCc1nc2cc(c(cc2[nH]1)C(F)(F)F)C(F)(F)F
InChI Key: InChIKey=HIBKAKWMRTWVTK-UHFFFAOYSA-N
Data: 7 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Voltage-gated calcium channel subunit alpha Cav2.2 (Homo sapiens (Human)) | BDBM164228 (US9688615, 39) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
SRMLSC US Patent | Assay Description Cells were plated in 384-well, clear-bottom, black-walled, poly-D-lysine coated plates (Becton Dickinson, Franklin Lake, N.J.) 2 days prior to use in... | US Patent US9688615 (2017) BindingDB Entry DOI: 10.7270/Q27S7KXH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-gated calcium channel subunit alpha Cav2.2 (Homo sapiens (Human)) | BDBM164228 (US9688615, 39) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
SRMLSC US Patent | Assay Description Cells were plated in 384-well, clear-bottom, black-walled, poly-D-lysine coated plates (Becton Dickinson, Franklin Lake, N.J.) 2 days prior to use in... | US Patent US9688615 (2017) BindingDB Entry DOI: 10.7270/Q27S7KXH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-gated T-type calcium channel (Homo sapiens (Human)) | BDBM164228 (US9688615, 39) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
SRMLSC US Patent | Assay Description Cells were plated in 384-well, clear-bottom, black-walled, poly-D-lysine coated plates (Becton Dickinson, Franklin Lake, N.J.) 2 days prior to use in... | US Patent US9688615 (2017) BindingDB Entry DOI: 10.7270/Q27S7KXH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calcium channel (Type L) (Homo sapiens (Human)) | BDBM164228 (US9688615, 39) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | 7.4 | n/a |
SRMLSC US Patent | Assay Description To assess the potential cardiac liability of compounds at an early stage in the drug discovery process, a Nav1.5 sodium channel screening assay was b... | US Patent US9688615 (2017) BindingDB Entry DOI: 10.7270/Q27S7KXH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human)) | BDBM164228 (US9688615, 39) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 680 | n/a | n/a | n/a | n/a | n/a | n/a |
SRMLSC US Patent | Assay Description Cells were plated in 384-well, clear-bottom, black-walled, poly-D-lysine coated plates (Becton Dickinson, Franklin Lake, N.J.) 2 days prior to use in... | US Patent US9688615 (2017) BindingDB Entry DOI: 10.7270/Q27S7KXH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calcium channel (Type L) (Homo sapiens (Human)) | BDBM164228 (US9688615, 39) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | 7.4 | n/a |
SRMLSC US Patent | Assay Description To assess the potential cardiac liability of compounds at an early stage in the drug discovery process, a Nav1.5 sodium channel screening assay was b... | US Patent US9688615 (2017) BindingDB Entry DOI: 10.7270/Q27S7KXH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human)) | BDBM164228 (US9688615, 39) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
SRMLSC US Patent | Assay Description Cells were plated in 384-well, clear-bottom, black-walled, poly-D-lysine coated plates (Becton Dickinson, Franklin Lake, N.J.) 2 days prior to use in... | US Patent US9688615 (2017) BindingDB Entry DOI: 10.7270/Q27S7KXH | |||||||||||
More data for this Ligand-Target Pair |