BDBM164661 US9067871, 139

SMILES: Fc1cccc(CC2C(CCc3ccc(OCCNS(=O)(=O)CC4CC4)cc23)N2CCC2)c1

InChI Key: InChIKey=CCAVNVYPXNXAMY-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 164661   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycine transporter 1 (Homo sapiens (Human))	BDBM164661 (US9067871, 139) Show SMILES Fc1cccc(CC2C(CCc3ccc(OCCNS(=O)(=O)CC4CC4)cc23)N2CCC2)c1 Show InChI InChI=1S/C26H33FN2O3S/c27-22-4-1-3-20(15-22)16-25-24-17-23(32-14-11-28-33(30,31)18-19-5-6-19)9-7-21(24)8-10-26(25)29-12-2-13-29/h1,3-4,7,9,15,17,19,25-26,28H,2,5-6,8,10-14,16,18H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair