BDBM164853 US9067871, 307

SMILES: CCNC1CCc2ccc(OCCNS(=O)(=O)CC3CC3)cc2C1Cc1cccc(Cl)c1

InChI Key: InChIKey=GNJHQCWYJKQCIT-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 164853   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycine transporter 1 (Homo sapiens (Human))	BDBM164853 (US9067871, 307) Show SMILES CCNC1CCc2ccc(OCCNS(=O)(=O)CC3CC3)cc2C1Cc1cccc(Cl)c1 Show InChI InChI=1S/C25H33ClN2O3S/c1-2-27-25-11-9-20-8-10-22(31-13-12-28-32(29,30)17-18-6-7-18)16-23(20)24(25)15-19-4-3-5-21(26)14-19/h3-5,8,10,14,16,18,24-25,27-28H,2,6-7,9,11-13,15,17H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair