BDBM165010 US9067917, 45::US9067917, 46::US9682971, 46

SMILES: OC(=O)[C@H]1CCCCC1c1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(OC(F)(F)F)cc1

InChI Key: InChIKey=ZNJOXPRVZKICEZ-AMVUTOCUSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 165010   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-lipoxygenase/FLAP (Homo sapiens (Human))	BDBM165010 (US9067917, 45 | US9067917, 46 | US9682971, 46) Show SMILES OC(=O)[C@H]1CCCCC1c1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(OC(F)(F)F)cc1 |r| Show InChI InChI=1S/C32H28F3N3O4/c33-32(34,35)42-23-13-9-20(10-14-23)18-38-29-16-15-24(41-19-22-12-11-21-5-1-4-8-27(21)36-22)17-28(29)37-30(38)25-6-2-3-7-26(25)31(39)40/h1,4-5,8-17,25-26H,2-3,6-7,18-19H2,(H,39,40)/t25?,26-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9682971 (2017) BindingDB Entry DOI: 10.7270/Q2P26W84
					More data for this Ligand-Target Pair
5-lipoxygenase/FLAP (Homo sapiens (Human))	BDBM165010 (US9067917, 45 | US9067917, 46 | US9682971, 46) Show SMILES OC(=O)[C@H]1CCCCC1c1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(OC(F)(F)F)cc1 |r| Show InChI InChI=1S/C32H28F3N3O4/c33-32(34,35)42-23-13-9-20(10-14-23)18-38-29-16-15-24(41-19-22-12-11-21-5-1-4-8-27(21)36-22)17-28(29)37-30(38)25-6-2-3-7-26(25)31(39)40/h1,4-5,8-17,25-26H,2-3,6-7,18-19H2,(H,39,40)/t25?,26-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9067917 (2015) BindingDB Entry DOI: 10.7270/Q24748M5
					More data for this Ligand-Target Pair
5-lipoxygenase/FLAP (Homo sapiens (Human))	BDBM165010 (US9067917, 45 | US9067917, 46 | US9682971, 46) Show SMILES OC(=O)[C@H]1CCCCC1c1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(OC(F)(F)F)cc1 |r| Show InChI InChI=1S/C32H28F3N3O4/c33-32(34,35)42-23-13-9-20(10-14-23)18-38-29-16-15-24(41-19-22-12-11-21-5-1-4-8-27(21)36-22)17-28(29)37-30(38)25-6-2-3-7-26(25)31(39)40/h1,4-5,8-17,25-26H,2-3,6-7,18-19H2,(H,39,40)/t25?,26-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9682971 (2017) BindingDB Entry DOI: 10.7270/Q2P26W84
					More data for this Ligand-Target Pair
5-lipoxygenase/FLAP (Homo sapiens (Human))	BDBM165010 (US9067917, 45 | US9067917, 46 | US9682971, 46) Show SMILES OC(=O)[C@H]1CCCCC1c1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(OC(F)(F)F)cc1 |r| Show InChI InChI=1S/C32H28F3N3O4/c33-32(34,35)42-23-13-9-20(10-14-23)18-38-29-16-15-24(41-19-22-12-11-21-5-1-4-8-27(21)36-22)17-28(29)37-30(38)25-6-2-3-7-26(25)31(39)40/h1,4-5,8-17,25-26H,2-3,6-7,18-19H2,(H,39,40)/t25?,26-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9067917 (2015) BindingDB Entry DOI: 10.7270/Q24748M5
					More data for this Ligand-Target Pair