BDBM165056 US9067917, 91::US9682971, 91

SMILES: OC(=O)C1(Cc2nc3cc(OCc4ccc5ccccc5n4)ccc3n2Cc2cccc(c2)-c2ccccc2)CCCC1

InChI Key: InChIKey=VGUFHKHUUFRLDH-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 165056   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-lipoxygenase/FLAP (Homo sapiens (Human))	BDBM165056 (US9067917, 91 | US9682971, 91) Show SMILES OC(=O)C1(Cc2nc3cc(OCc4ccc5ccccc5n4)ccc3n2Cc2cccc(c2)-c2ccccc2)CCCC1 Show InChI InChI=1S/C37H33N3O3/c41-36(42)37(19-6-7-20-37)23-35-39-33-22-31(43-25-30-16-15-28-12-4-5-14-32(28)38-30)17-18-34(33)40(35)24-26-9-8-13-29(21-26)27-10-2-1-3-11-27/h1-5,8-18,21-22H,6-7,19-20,23-25H2,(H,41,42)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9682971 (2017) BindingDB Entry DOI: 10.7270/Q2P26W84
					More data for this Ligand-Target Pair
5-lipoxygenase/FLAP (Homo sapiens (Human))	BDBM165056 (US9067917, 91 | US9682971, 91) Show SMILES OC(=O)C1(Cc2nc3cc(OCc4ccc5ccccc5n4)ccc3n2Cc2cccc(c2)-c2ccccc2)CCCC1 Show InChI InChI=1S/C37H33N3O3/c41-36(42)37(19-6-7-20-37)23-35-39-33-22-31(43-25-30-16-15-28-12-4-5-14-32(28)38-30)17-18-34(33)40(35)24-26-9-8-13-29(21-26)27-10-2-1-3-11-27/h1-5,8-18,21-22H,6-7,19-20,23-25H2,(H,41,42)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9067917 (2015) BindingDB Entry DOI: 10.7270/Q24748M5
					More data for this Ligand-Target Pair